Announcement: Metformin: Wonderous diabetes drug or not?


metformin Announcement: Metformin: Wonderous diabetes drug or not?Its simply known as Metformin, or by its brand names which include: Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet, It is the most prescribed Oral medication of choice for people with type 2 diabetes to help control their blood sugars.

Metformin has shown to hold some promise in the prevention of tobacco-induced lung cancer as well and its potential benefits do not end there, I for one take about 2000mg of these little pills a day, but it wasn’t until a bad experience with my Metformin prescription recently that I decided to delve further into the inner workings of this drug.

For many we accept  these drugs that heal what ails us  with little or no challenge over the usual allergic reaction issues, but sometimes the risk vs rewards ratio encompasses a lot more and here is why.

A few months ago I received a New Metformin prescription from my doctor, It wasn’t anything New, just a renewal, I have been on Metformin for about 4 years now and it has been working great at controlling my blood sugars.

Something was off about this batch though, as soon as I started taking the Metformin dose, my blood sugars went haywire, In the first week, I experienced high’s on 5 of the seven days.

After years living with diabetes, it is natural to sometimes get a little lax with diabetes management, and  this could have been a legitimate reason for what was going on with me at this time but I just couldn’t shake the notion that  my unusual highs had something to do with that Metformin prescription. When I voiced  my concerns to the Endo, he quickly switched the Metformin and had me keep more of a closer eye on my blood glucose numbers.

Its taken me a few months to get back to my regular diabetic self but my curiosity was peaked to try and explain why?

Did I merely get a bad batch of Metformin?, had someone tampered with my prescription (a life fear of mine after the Chicago Tylenol murders and that case remains unsolved)?, Maybe I had been given a placebo?, I surely had to know.

Since I am surely lacking one of those Beckman-Coulter Array 360 Protein and Special Chemistry Analyzer thingy and couldn’t channel my inner Mcgyver, I did what most of us Insomniac cooks do when faced by such Metformin dilemmas, I took to Google.

drug analysers 300x263 Announcement: Metformin: Wonderous diabetes drug or not?

Beckman-Coulter Array 360 Analyzer

And here are the five things I learned about Metformin.

1. Anyone can manufacture Metformin since the patent for its brand name has expired

2. The FDA only requires that Generic Metformin contain the identical active ingredient at the same dosage as the brand name product, however it  allows colors, flavors and other inactive ingredients to vary between manufacturers.

3. All branded Metformin have a generic name (Metformin) in this case

4. The Approval process for the generic Metformin is not as stringent as the Original brand name Metformin.

5. There are 7 different Manufacturers for Metformin.

  • GlaxoSmithKline
  • Andrx Laboratories, Inc
  • Bristol Myers Squibb
  • Par Pharmaceutical, Inc.
  • Watson Laboratories, Inc
  • Mylan Pharmaceuticals, Inc.
  • Sumitomo Pharmaceuticals

Now I am not one to complain especially since my Metformin comes free thanks to Giant Eagle, and I am a trusting kinda a fellow so I tend to believe that the FDA has a handle on things and my Metformin is Safe but I cant help but wonder, with all those Metformin manufacturers out there, how exactly did I end up with a free Metformin pill and what exactly constitutes an inactive ingredient in it or am I just….

pharmaceutical roulette 297x300 Announcement: Metformin: Wonderous diabetes drug or not?

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  1. I don’t know anything about Metformin, but I am happy that so many of you are trying it and writing about it. It’s the best way for the rest of us to learn.

  2. No, I believe you are right in questioning what is going on. Manufacturers do make mistakes and some do slip through quality control. Most won’t admit it, but I know it happens.

    I think I am lucky in that when my pharmacy changes manufacturers, it does tell me that the supplier has changed and to which one. I am told to watch for any changes from my normal reactions (normally none) and report if I have any reactions. Only had one in the seven years and was immediately reissued a refill and asked to return to original (which I did). There was something wrong and it was corrected at no cost to me. I am very thankful. This was on a blood pressure drug.

  3. WOW! Thank you for sharing this article. I just started taking Metformin again after 16 years. How do I find out who manufactures mine? The Pharmacy?

    • Yes the pharmacist will tell you who manufactures your Metformin, then just do your due diligence from there, its always good to know because its true Quality control standards sometimes vary from one to the other.

  4. I am on Metformin as well. Mine is manufactured by GlaxoSmithKline and it’s not effective for me as anything other than a maximum strength laxative unless I take it with the Glipizide i’m on.

    • Thanks for sharing K. Its true there are different Metformin manufacturers and one never knows with each different Quality control departments just how different the effectiveness of the drug is…:)

  5. We should always know what we’re taking, where it comes from and if it causes any side effects. A new natural medication, Sucanon will be available for sale in US and Canada in Feb 2012.
    It helps your body improve the use of its own insulin, reducing type 2 diabetes symptoms. Clinical tests show no adverse effects.


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